5-methyltetrahydrofolate--homocysteine S-methyltransferase

Details

Name
5-methyltetrahydrofolate--homocysteine S-methyltransferase
Kind
protein
Synonyms
  • EC 2.1.1.13
Gene Name
Not Available
UniProtKB Entry
Q2RJ67TrEMBL
Organism
Moorella thermoacetica (strain ATCC 39073)
NCBI Taxonomy ID
264732
Amino acid sequence
>lcl|BSEQ0019338|5-methyltetrahydrofolate--homocysteine S-methyltransferase
MPTYEELSQAVFEGDEAQVVELTRSLLSGGAEPLEVINKGLIAGMDRVGVLFKNNEMFVP
EVLMSANAMNAGVEVVKQSQQAFDMPSVGKIVLGTVKGDLHDIGKNLVAMMLESGGFTVY
NLGVDIEPGKFVEAVKKYQPDIVGMSALLTTTMMNMKSTIDALIAAGLRDRVKVIVGGAP
LSQDFADEIGADGYAPDAASATELCRQLLE
Number of residues
210
Molecular Weight
22329.605
Theoretical pI
4.18
GO Classification
Functions
cobalamin binding / cobalt ion binding / methionine synthase activity
Processes
methanogenesis
General Function
Not Available
Specific Function
cobalamin binding
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Not Available
Gene sequence
>lcl|BSEQ0019339|5-methyltetrahydrofolate--homocysteine S-methyltransferase
ATGCCCACTTATGAAGAACTCTCCCAGGCGGTATTTGAAGGTGATGAAGCACAGGTGGTG
GAATTGACCAGGAGTTTGTTGAGCGGCGGAGCGGAACCCCTGGAAGTGATCAATAAAGGT
CTGATCGCAGGTATGGACCGGGTCGGCGTCCTGTTCAAGAACAACGAGATGTTCGTCCCT
GAGGTCTTAATGTCGGCCAACGCCATGAACGCCGGGGTGGAGGTTGTTAAGCAGAGCCAG
CAAGCCTTTGACATGCCGTCCGTGGGAAAAATCGTACTGGGAACCGTTAAGGGGGACCTG
CACGACATCGGCAAGAACCTGGTGGCCATGATGTTGGAGAGCGGCGGCTTCACGGTTTAC
AACCTGGGGGTGGACATCGAACCGGGTAAATTCGTAGAGGCGGTAAAGAAGTACCAGCCG
GACATCGTGGGCATGTCCGCCCTGTTAACCACCACCATGATGAATATGAAATCAACCATC
GATGCCCTGATCGCCGCCGGGCTGAGGGATCGGGTAAAAGTAATCGTCGGCGGGGCGCCC
CTCAGCCAGGATTTTGCAGATGAGATCGGAGCCGACGGGTATGCTCCGGACGCCGCTTCG
GCCACCGAGCTCTGCAGGCAGCTGCTTGAGTAA
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ2RJ67
UniProtKB Entry NameQ2RJ67_MOOTA
GenBank Gene IDCP000232
PDB ID(s)1Y80
KEGG IDmta:Moth_1208
NCBI Gene ID3832975
General References
  1. Pierce E, Xie G, Barabote RD, Saunders E, Han CS, Detter JC, Richardson P, Brettin TS, Das A, Ljungdahl LG, Ragsdale SW: The complete genome sequence of Moorella thermoacetica (f. Clostridium thermoaceticum). Environ Microbiol. 2008 Oct;10(10):2550-73. doi: 10.1111/j.1462-2920.2008.01679.x. Epub 2008 Jun 9. [Article]

Associated Data

Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Vitamin B 12 factor IIImexperimentalunknowntargetDetails