Immunoglobulin heavy constant gamma 1

BE0002815ProteinHumansIGHG1

Constant region of immunoglobulin (Ig) heavy chains. It is acted on by 25 drugs in DrugBank.

Gene name
IGHG1
UniProtKB entry
P01857Swiss-Prot
Cellular location
Secreted
Residues / weight
399 residues · 43,912 Da
Also known as
Ig gamma-1 chain C region · Ig gamma-1 chain C region EU · Ig gamma-1 chain C region KOL · Ig gamma-1 chain C region NIE

Resolves to

Protein
UniProtP01857UniProt nameIGHG1_HUMAN
Gene
HGNCHGNC:5525GeneCardsIGHG1
Structure
PDB1AJ7PDB1AQKPDB1AXS
Drugs

What you can answer from here — as of September 03, 2024

25DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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8GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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40+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Immunoglobulin heavy constant gamma 1, how selective are they, and which programs against it are still in active trials?

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