Diadenosine hexaphosphate hydrolase

BE0002822ProteinThermus thermophilusndx1

Specifically hydrolyzes (di)adenosine polyphosphates but not ATP or diadenosine triphosphate, generating ATP as the product. It is acted on by 1 drug in DrugBank.

Gene name
ndx1
UniProtKB entry
Q75UV1Swiss-Prot
Residues / weight
126 residues · 14,170 Da
Also known as
3.6.1.61 · Ap6A hydrolase · ATP-generating (di)nucleotide polyphosphate hydrolase · ATP-generating Ap6A hydrolase · Nudix protein

Resolves to

Protein
UniProtQ75UV1UniProt nameNDX1_THETH
Gene
NCBI Gene3169127
Pharmacology
KEGGttj:TTHA1880
Structure
PDB1VC8PDB1VC9PDB1VCD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
3GO termsFunction, process and component, as structured annotations
Sign in
1+ReferenceStructured and connected to the statements they support
Sign in

Which compounds in development act on Diadenosine hexaphosphate hydrolase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In