Beta-2-glycoprotein 1

BE0002854ProteinHumansAPOH

Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. It is acted on by 4 drugs in DrugBank.

Gene name
APOH
UniProtKB entry
P02749Swiss-Prot
Cellular location
Secreted
Residues / weight
345 residues · 38,298 Da
Also known as
Activated protein C-binding protein · Anticardiolipin cofactor · APC inhibitor · Apo-H · Apolipoprotein H

Resolves to

Protein
UniProtP02749UniProt nameAPOH_HUMAN
Gene
HGNCHGNC:616NCBI Gene350GeneCardsAPOH
Pharmacology
KEGGhsa:350
Structure
PDB1C1ZPDB1G4FPDB1G4G
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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25GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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32+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Beta-2-glycoprotein 1, how selective are they, and which programs against it are still in active trials?

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