Interleukin-6 receptor subunit alpha

BE0002859ProteinHumansIL6R

Part of the receptor for interleukin 6. It is acted on by 6 drugs in DrugBank.

Gene name
IL6R
UniProtKB entry
P08887Swiss-Prot
Cellular location
Cell membrane
Residues / weight
468 residues · 51,547 Da
Also known as
gp80 · IL-6 receptor subunit alpha · IL-6R 1 · IL-6R subunit alpha · IL-6R-alpha

Resolves to

Protein
UniProtP08887UniProt nameIL6RA_HUMAN
Gene
HGNCHGNC:6019NCBI Gene3570GeneCardsIL6R
Pharmacology
IUPHAR/GtoPdb1708KEGGhsa:3570
Structure
PDB1N26PDB1P9MPDB2ARW
Drugs

What you can answer from here — as of September 07, 2019

6DrugsApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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30GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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30+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-6 receptor subunit alpha, how selective are they, and which programs against it are still in active trials?

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