Sulfite oxidase, mitochondrial

BE0002927ProteinHumansSUOX

Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids (By similarity). It is acted on by 4 drugs in DrugBank.

Gene name
SUOX
UniProtKB entry
P51687Swiss-Prot
Cellular location
Mitochondrion intermembrane space
Residues / weight
545 residues · 60,283 Da
Also known as
1.8.3.1 · HSO · Nitrite reductase, mitochondrial

Resolves to

Protein
UniProtP51687UniProt nameSUOX_HUMAN
Gene
HGNCHGNC:11460NCBI Gene6821GeneCardsSUOX
Pharmacology
KEGGhsa:6821
Structure
PDB1MJ4
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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15+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Sulfite oxidase, mitochondrial, how selective are they, and which programs against it are still in active trials?

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