Immunoglobulin lambda variable 2-8

BE0002939ProteinHumansIGLV2-8

V region of the variable domain of immunoglobulin light chains that participates in the antigen recognition (PubMed:24600447). It is acted on by 1 drug in DrugBank.

Gene name
IGLV2-8
UniProtKB entry
P01709Swiss-Prot
Cellular location
Secreted
Residues / weight
118 residues · 12,382 Da
Also known as
Ig lambda chain V-II region BO · Ig lambda chain V-II region MGC

Resolves to

Protein
UniProtP01709UniProt nameLV208_HUMAN
Gene
HGNCHGNC:5895GeneCardsIGLV2-8
Structure
PDB1A8JPDB1DCLPDB1MCW
Drugs

What you can answer from here — as of September 03, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Immunoglobulin lambda variable 2-8, how selective are they, and which programs against it are still in active trials?

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