Pol polyprotein

BE0003079ProteinEIAVpol

During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. It is acted on by 1 drug in DrugBank.

Gene name
pol
UniProtKB entry
P03371Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
1,145 residues · 129,519 Da
Also known as
2.7.7.49 · RT

Resolves to

Protein
UniProtP03371UniProt namePOL_EIAVY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
11GO termsFunction, process and component, as structured annotations
Sign in
7Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Pol polyprotein, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In