Antigen peptide transporter 1

BE0003109ProteinHumansTAP1

ABC transporter associated with antigen processing. It is acted on by 1 drug in DrugBank.

Gene name
TAP1
UniProtKB entry
Q03518Swiss-Prot
Cellular location
Endoplasmic reticulum membrane
Residues / weight
748 residues · 80,964 Da
Also known as
7.4.2.14 · ABCB2 · APT1 · ATP-binding cassette sub-family B member 2 · Peptide supply factor 1

Resolves to

Protein
UniProtQ03518UniProt nameTAP1_HUMAN
Gene
HGNCHGNC:43NCBI Gene6890GeneCardsTAP1
Pharmacology
KEGGhsa:6890
Structure
PDB1JJ7PDB5U1DPDB8T46
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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14GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Antigen peptide transporter 1, how selective are they, and which programs against it are still in active trials?

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