Peroxiredoxin

BE0003140ProteinPlasmodium falciparum (isolate 3D7)prx

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. It is acted on by 2 drugs in DrugBank.

Gene name: prx
UniProtKB entry: Q5MYR6TrEMBL
Residues / weight: 240 residues · 28,124 Da
Also known as: 1-cys peroxiredoxin · PfAOP

Resolves to

Protein

UniProtQ5MYR6UniProt nameQ5MYR6_PLAF7

Gene

NCBI Gene2655035

Pharmacology

KEGGpfa:MAL7P1.159

Structure

PDB1XIYPDB4D73

Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action

3GO termsFunction, process and component, as structured annotations

1Pfam domainDomain architecture mapped to Pfam families and clans

6+ReferencesStructured and connected to the statements they support

Which approved drugs act on Peroxiredoxin, how selective are they, and which programs against it are still in active trials?

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