Placenta growth factor

BE0003148ProteinHumansPGF

Growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. It is acted on by 3 drugs in DrugBank.

Gene name
PGF
UniProtKB entry
P49763Swiss-Prot
Cellular location
Secreted
Residues / weight
221 residues · 24,788 Da
Also known as
PGFL · PLGF

Resolves to

Protein
UniProtP49763UniProt namePLGF_HUMAN
Gene
HGNCHGNC:8893NCBI Gene5228GeneCardsPGF
Pharmacology
KEGGhsa:5228
Structure
PDB1FZVPDB1RV6
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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6GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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20+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Placenta growth factor, how selective are they, and which programs against it are still in active trials?

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