Pituitary adenylate cyclase-activating polypeptide

BE0003199ProteinHumansADCYAP1

PACAP is a neuropeptide involved in diverse array of physiological processes through activating the PACAP subfamily of class B1 G protein-coupled receptors: VIP receptor 1 (VIPR1), VIP receptor 2 (VIPR2), and PACAP type I receptor... It is acted on by 1 drug in DrugBank.

Gene name
ADCYAP1
UniProtKB entry
P18509Swiss-Prot
Cellular location
Secreted
Residues / weight
176 residues · 18,835 Da
Also known as
PACAP

Resolves to

Protein
UniProtP18509UniProt namePACA_HUMAN
Gene
HGNCHGNC:241NCBI Gene116GeneCardsADCYAP1
Pharmacology
KEGGhsa:116
Structure
PDB1GEAPDB2D2PPDB2JOD
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1Clinical trialTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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11+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Pituitary adenylate cyclase-activating polypeptide, and which indications are they being tested in?

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