N-succinylamino acid racemase

BE0003211ProteinDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)

Acts as a N-succinylamino acid racemase (NSAR) that catalyzes the racemization of N-succinyl-L-phenylglycine and N-succinyl-D/L-phenylalanine (PubMed:24872444, PubMed:25875730). It is acted on by 1 drug in DrugBank.

UniProtKB entry
Q9RYA6TrEMBL
Residues / weight
375 residues · 40,900 Da
Also known as
4-(2'-carboxyphenyl)-4-oxybutyric acid synthase · 4.2.1.113 · 5.1.1.- · N-acylamino acid racemase · NAAAR

Resolves to

Protein
UniProtQ9RYA6UniProt nameNSAR_DEIRA
Gene
NCBI Gene1799680
Pharmacology
KEGGdra:DR_0044
Structure
PDB1R0MPDB1XPYPDB1XS2
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on N-succinylamino acid racemase, and which indications are they being tested in?

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