ATP-dependent protease ATPase subunit HslU

BE0003289ProteinShigella flexnerihslU

ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. It is acted on by 1 drug in DrugBank.

Gene name
hslU
UniProtKB entry
P0A6H7Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
443 residues · 49,593 Da
Also known as
Heat shock protein HslU · htpI · Unfoldase HslU

Resolves to

Protein
UniProtP0A6H7UniProt nameHSLU_SHIFL
Gene
NCBI Gene1025162
Pharmacology
KEGGsfl:SF4009
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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2+ReferencesStructured and connected to the statements they support
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Which compounds in development act on ATP-dependent protease ATPase subunit HslU, and which indications are they being tested in?

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