Type II secretion system ATPase E

BE0003292ProteinVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)epsE

ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. It is acted on by 1 drug in DrugBank.

Gene name
epsE
UniProtKB entry
P37093Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
503 residues · 56,358 Da
Also known as
7.4.2.8 · Cholera toxin secretion protein EpsE · General secretion pathway protein E · T2SS protein E · Type II secretion system protein E

Resolves to

Protein
UniProtP37093UniProt nameGSPE_VIBCH
Gene
NCBI Gene2614895
Pharmacology
KEGGvch:VC2732
Structure
PDB1P9RPDB1P9WPDB2BH1
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
2+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Type II secretion system ATPase E, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In