Integrin beta-4

BE0003298ProteinHumansITGB4

Integrin alpha-6/beta-4 is a receptor for laminin. It is acted on by 1 drug in DrugBank.

Gene name
ITGB4
UniProtKB entry
P16144Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,822 residues · 202,165 Da
Also known as
GP150

Resolves to

Protein
UniProtP16144UniProt nameITB4_HUMAN
Gene
HGNCHGNC:6158NCBI Gene3691GeneCardsITGB4
Pharmacology
KEGGhsa:3691
Structure
PDB1QG3PDB2YRZPDB3F7P
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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7Pfam domainsDomain architecture mapped to Pfam families and clans
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31+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Integrin beta-4, and which indications are they being tested in?

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