dTDP-4-dehydrorhamnose 3,5-epimerase

BE0003322ProteinMycobacterium tuberculosisrmlC

Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. It is acted on by 1 drug in DrugBank.

Gene name
rmlC
UniProtKB entry
P9WH11Swiss-Prot
Residues / weight
202 residues · 22,314 Da
Also known as
5.1.3.13 · dTDP-4-keto-6-deoxyglucose 3,5-epimerase · dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase · dTDP-L-rhamnose synthase · strM

Resolves to

Protein
UniProtP9WH11UniProt nameRMLC_MYCTU
Gene
NCBI Gene887352
Pharmacology
KEGGmtu:Rv3465
Structure
PDB1PM7PDB1UPIPDB2IXC
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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7+ReferencesStructured and connected to the statements they support
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Which compounds in development act on dTDP-4-dehydrorhamnose 3,5-epimerase, and which indications are they being tested in?

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