Glutaminyl-peptide cyclotransferase

BE0003330ProteinHumansQPCT

Responsible for the biosynthesis of pyroglutamyl peptides. It is acted on by 4 drugs in DrugBank.

Gene name
QPCT
UniProtKB entry
Q16769Swiss-Prot
Cellular location
Secreted
Residues / weight
361 residues · 40,876 Da
Also known as
2.3.2.5 · EC · Glutaminyl cyclase · Glutaminyl-tRNA cyclotransferase · Glutamyl cyclase

Resolves to

Protein
UniProtQ16769UniProt nameQPCT_HUMAN
Gene
HGNCHGNC:9753NCBI Gene25797GeneCardsQPCT
Pharmacology
IUPHAR/GtoPdb2411KEGGhsa:25797
Structure
PDB2AFMPDB2AFOPDB2AFS
Drugs

What you can answer from here — as of September 07, 2019

4DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
5GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
15+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Glutaminyl-peptide cyclotransferase, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In