Arginine deiminase
Details
- Name
- Arginine deiminase
- Kind
- protein
- Synonyms
- 3.5.3.6
- AD
- ADI
- Arginine dihydrolase
- Gene Name
- arcA
- UniProtKB Entry
- P13981Swiss-Prot
- Organism
- Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
- NCBI Taxonomy ID
- 208964
- Amino acid sequence
>lcl|BSEQ0012341|Arginine deiminase MSTEKTKLGVHSEAGKLRKVMVCSPGLAHQRLTPSNCDELLFDDVIWVNQAKRDHFDFVT KMRERGIDVLEMHNLLTETIQNPEALKWILDRKITADSVGLGLTSELRSWLESLEPRKLA EYLIGGVAADDLPASEGANILKMYREYLGHSSFLLPPLPNTQFTRDTTCWIYGGVTLNPM YWPARRQETLLTTAIYKFHPEFANAEFEIWYGDPDKDHGSSTLEGGDVMPIGNGVVLIGM GERSSRQAIGQVAQSLFAKGAAERVIVAGLPKSRAAMHLDTVFSFCDRDLVTVFPEVVKE IVPFSLRPDPSSPYGMNIRREEKTFLEVVAESLGLKKLRVVETGGNSFAAEREQWDDGNN VVCLEPGVVVGYDRNTYTNTLLRKAGVEVITISASELGRGRGGGHCMTCPIVRDPIDY
- Number of residues
- 418
- Molecular Weight
- 46435.635
- Theoretical pI
- 5.5
- GO Classification
- Functionsarginine deiminase activityProcessesarginine catabolic process to ornithine / arginine deiminase pathway / protein citrullinationComponentscytoplasm
- General Function
- Not Available
- Specific Function
- arginine deiminase activity
- Pfam Domain Function
- Not Available
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0012342|Arginine deiminase (arcA) ATGAGCACGGAAAAAACCAAACTTGGCGTCCACTCCGAAGCCGGCAAACTGCGCAAAGTG ATGGTCTGCTCGCCCGGACTCGCCCACCAGCGCCTGACCCCGAGCAACTGCGACGAGTTG CTGTTCGACGACGTGATCTGGGTGAACCAGGCCAAGCGCGACCACTTCGACTTCGTCACC AAGATGCGCGAGCGCGGCATCGACGTCCTCGAGATGCACAATCTGCTGACCGAGACCATC CAGAACCCGGAAGCGCTGAAGTGGATCCTCGATCGCAAGATCACCGCCGACAGCGTCGGC CTGGGCCTGACCAGCGAGCTGCGCTCCTGGCTGGAGAGCCTGGAGCCGCGCAAGCTGGCC GAGTACCTGATCGGCGGCGTCGCCGCTGACGACCTGCCCGCCAGCGAAGGCGCCAACATC CTCAAGATGTACCGCGAGTACCTGGGCCATTCCAGCTTCCTGCTGCCGCCGTTGCCGAAC ACCCAGTTCACCCGCGACACCACTTGCTGGATCTACGGCGGCGTGACCCTGAACCCGATG TACTGGCCGGCGCGACGACAGGAAACCCTGCTGACCACCGCCATCTACAAGTTCCACCCC GAGTTCGCCAACGCCGAGTTCGAGATCTGGTACGGCGACCCGGACAAGGACCACGGCTCC TCGACCCTGGAAGGCGGCGACGTGATGCCGATCGGCAACGGCGTGGTCCTGATCGGCATG GGCGAGCGCTCCTCGCGCCAGGCCATCGGTCAGGTCGCCCAGTCGCTGTTCGCCAAGGGC GCCGCCGAGCGGGTGATCGTCGCCGGCCTGCCGAAGTCCCGCGCCGCGATGCACCTGGAC ACCGTGTTCAGCTTCTGCGACCGCGACCTGGTCACGGTCTTCCCGGAAGTGGTCAAGGAA ATCGTGCCCTTCAGCCTGCGCCCCGATCCGAGCAGCCCCTACGGCATGAACATCCGCCGC GAGGAGAAAACCTTCCTCGAAGTGGTCGCCGAATCCCTCGGCCTGAAGAAACTGCGCGTG GTCGAGACCGGCGGCAACAGCTTCGCCGCCGAGCGCGAGCAATGGGACGACGGTAACAAC GTGGTCTGCCTGGAGCCGGGCGTGGTGGTCGGCTACGACCGCAACACCTACACCAACACC CTGCTGCGCAAGGCCGGCGTCGAGGTCATCACCATCAGCGCCAGCGAACTGGGTCGCGGT CGCGGCGGCGGCCACTGCATGACCTGCCCGATCGTCCGCGACCCGATCGACTACTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P13981 UniProtKB Entry Name ARCA_PSEAE GenBank Gene ID X14694 PDB ID(s) 1RXX, 2A9G, 2AAF, 2ABR, 2ACI KEGG ID pae:PA5171 NCBI Gene ID 881801 - General References
- Baur H, Luethi E, Stalon V, Mercenier A, Haas D: Sequence analysis and expression of the arginine-deiminase and carbamate-kinase genes of Pseudomonas aeruginosa. Eur J Biochem. 1989 Jan 15;179(1):53-60. [Article]
- Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV: Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000 Aug 31;406(6799):959-64. [Article]
- Luthi E, Baur H, Gamper M, Brunner F, Villeval D, Mercenier A, Haas D: The arc operon for anaerobic arginine catabolism in Pseudomonas aeruginosa contains an additional gene, arcD, encoding a membrane protein. Gene. 1990 Mar 1;87(1):37-43. [Article]
Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details [(1S)-4-[[Amino-[(2R)-2-amino-2-carboxyethyl]sulfanylmethylidene]amino]-1-carboxybutyl]azanium experimental unknown target Details