Proteasome subunit alpha

BE0003353ProteinMycobacterium tuberculosisprcA

Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. It is acted on by 1 drug in DrugBank.

Gene name
prcA
UniProtKB entry
P9WHU1Swiss-Prot
Cellular location
Cytoplasm
Residues / weight
248 residues · 26,881 Da
Also known as
20S proteasome alpha subunit · 3.4.25.1 · Proteasome core protein PrcA

Resolves to

Protein
UniProtP9WHU1UniProt namePSA_MYCTU
Gene
NCBI Gene887538
Pharmacology
KEGGmtu:Rv2109c
Structure
PDB2FHGPDB2FHHPDB3H6F
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Proteasome subunit alpha, and which indications are they being tested in?

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