DNA-directed RNA polymerase subunit alpha

BE0003366ProteinThermus thermophilusrpoA

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is acted on by 1 drug in DrugBank.

Gene name
rpoA
UniProtKB entry
Q9Z9H6Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
315 residues · 35,013 Da
Also known as
2.7.7.6 · RNA polymerase subunit alpha · RNAP subunit alpha · Transcriptase subunit alpha

Resolves to

Protein
UniProtQ9Z9H6UniProt nameRPOA_THETH
Structure
PDB1DOQPDB1IW7PDB1SMY
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
4GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on DNA-directed RNA polymerase subunit alpha, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In