DNA-directed RNA polymerase subunit omega

BE0003369ProteinThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)rpoZ

Promotes RNA polymerase assembly. It is acted on by 2 drugs in DrugBank.

Gene name
rpoZ
UniProtKB entry
Q8RQE7Swiss-Prot
Cellular location
Cytoplasmic
Residues / weight
99 residues · 11,517 Da
Also known as
2.7.7.6 · RNA polymerase omega subunit · RNAP omega subunit · Transcriptase subunit omega

Resolves to

Protein
UniProtQ8RQE7UniProt nameRPOZ_THET8
Gene
NCBI Gene3169896
Pharmacology
KEGGttj:TTHA1561
Structure
PDB1IW7PDB1SMYPDB1ZYR
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on DNA-directed RNA polymerase subunit omega, and which indications are they being tested in?

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