Leptin receptor

BE0003376ProteinHumansLEPR

Receptor for hormone LEP/leptin (Probable) (PubMed:22405007). It is acted on by 3 drugs in DrugBank.

Gene name
LEPR
UniProtKB entry
P48357Swiss-Prot
Cellular location
Cell membrane
Residues / weight
1,165 residues · 132,493 Da
Also known as
DB · HuB219 · LEP-R · OB receptor · OB-R

Resolves to

Protein
UniProtP48357UniProt nameLEPR_HUMAN
Gene
HGNCHGNC:6554NCBI Gene3953GeneCardsLEPR
Pharmacology
KEGGhsa:3953
Structure
PDB3V6OPDB6E2PPDB7Z3Q
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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25GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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24+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Leptin receptor, how selective are they, and which programs against it are still in active trials?

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