Endothelin-1

BE0003384ProteinHumansEDN1

Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). It is acted on by 2 drugs in DrugBank.

Gene name
EDN1
UniProtKB entry
P05305Swiss-Prot
Cellular location
Secreted
Residues / weight
212 residues · 24,425 Da
Also known as
PPET1 · Preproendothelin-1

Resolves to

Protein
UniProtP05305UniProt nameEDN1_HUMAN
Gene
HGNCHGNC:3176NCBI Gene1906GeneCardsEDN1
Pharmacology
KEGGhsa:1906
Structure
PDB1EDNPDB1EDPPDB1T7H
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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6Clinical trialsTrials of drugs acting on it, by phase and status
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49GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endothelin-1, and which indications are they being tested in?

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