Penicillin-binding protein 1A

BE0003395ProteinStreptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)ponA

Cell wall formation. It is acted on by 2 drugs in DrugBank.

Gene name
ponA
UniProtKB entry
Q04707Swiss-Prot
Cellular location
Secreted
Residues / weight
719 residues · 79,758 Da
Also known as
PBP-1A

Resolves to

Protein
UniProtQ04707UniProt namePBPA_STRPN
Pharmacology
KEGGspn:SP_0369
Structure
PDB2ZC5PDB2ZC6
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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7GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Penicillin-binding protein 1A, how selective are they, and which programs against it are still in active trials?

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