Peptidoglycan D,D-transpeptidase FtsI

BE0003396ProteinEscherichia coli O157:H7ftsI

Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. It is acted on by 1 drug in DrugBank.

Gene name
ftsI
UniProtKB entry
P0AD69Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
588 residues · 63,877 Da
Also known as
3.4.16.4 · PBP-3 · pbpB · Penicillin-binding protein 3

Resolves to

Protein
UniProtP0AD69UniProt nameFTSI_ECO57
Gene
NCBI Gene913535
Pharmacology
KEGGece:Z0094
Drugs

What you can answer from here — as of September 04, 2024

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Peptidoglycan D,D-transpeptidase FtsI, and which indications are they being tested in?

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