Tubulin beta-2B chain

BE0003401ProteinHumansTUBB2B

Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:23001566, PubMed:26732629, PubMed:28013290). It is acted on by 2 drugs in DrugBank.

Gene name
TUBB2B
UniProtKB entry
Q9BVA1Swiss-Prot
Cellular location
Cytoplasm, cytoskeleton
Residues / weight
445 residues · 49,953 Da

Resolves to

Protein
UniProtQ9BVA1UniProt nameTBB2B_HUMAN
Gene
HGNCHGNC:30829NCBI Gene347733GeneCardsTUBB2B
Pharmacology
KEGGhsa:347733
Structure
PDB6E7CPDB7ZCWPDB9OX7
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tubulin beta-2B chain, and which indications are they being tested in?

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