Disintegrin and metalloproteinase domain-containing protein 9

BE0003412ProteinHumansADAM9

Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. It is acted on by 1 drug in DrugBank.

Gene name
ADAM9
UniProtKB entry
Q13443Swiss-Prot
Cellular location
Cell membrane
Residues / weight
819 residues · 90,555 Da
Also known as
3.4.24.- · ADAM 9 · Cellular disintegrin-related protein · KIAA0021 · MCMP

Resolves to

Protein
UniProtQ13443UniProt nameADAM9_HUMAN
Gene
HGNCHGNC:216NCBI Gene8754GeneCardsADAM9
Pharmacology
IUPHAR/GtoPdb1657KEGGhsa:8754
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
31GO termsFunction, process and component, as structured annotations
Sign in
4Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
9+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Disintegrin and metalloproteinase domain-containing protein 9, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In