Type-2 angiotensin II receptor

BE0003426ProteinHumansAGTR2

Receptor for angiotensin II, a vasoconstricting peptide (PubMed:28379944, PubMed:29967536, PubMed:31899086, PubMed:8185599). It is acted on by 8 drugs in DrugBank.

Gene name
AGTR2
UniProtKB entry
P50052Swiss-Prot
Cellular location
Cell membrane
Residues / weight
363 residues · 41,183 Da
Also known as
Angiotensin II type-2 receptor · AT2 receptor

Resolves to

Protein
UniProtP50052UniProt nameAGTR2_HUMAN
Gene
HGNCHGNC:338NCBI Gene186GeneCardsAGTR2
Pharmacology
IUPHAR/GtoPdb35KEGGhsa:186
Structure
PDB5UNFPDB5UNGPDB5UNH
Drugs

What you can answer from here — as of September 07, 2019

8DrugsApproved to experimental, with action, bond type and pharmacological action
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18GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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34+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Type-2 angiotensin II receptor, how selective are they, and which programs against it are still in active trials?

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