Centromere-associated protein E
Details
- Name
- Centromere-associated protein E
- Kind
- protein
- Synonyms
- CENP-E
- Centromere protein E
- Kinesin-7
- Kinesin-related protein CENPE
- Gene Name
- CENPE
- UniProtKB Entry
- Q02224Swiss-Prot
- Organism
- Humans
- NCBI Taxonomy ID
- 9606
- Amino acid sequence
>lcl|BSEQ0006699|Centromere-associated protein E MAEEGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTK NVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGSEDHLGVIPRAIHDIFQKIKKF PDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALK WITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAGSE RAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNA KTRIICTITPVSFDETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLE EVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRR VTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLS EIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEAL ERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDS QKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELAT TYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEG KITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL FSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD LEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMT IENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQ QQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITK ERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDS TTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQ ESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSV AKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNL SEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAK DSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKM KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEE MRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKL RGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEK TDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQS LTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDL EIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKEL QLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKE RDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRI KELLKRYSEMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQ RCSMEFHRIMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCD VPSRELRDLKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRF DIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNE KLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHK ESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDL KMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTD PQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQHL SNEVKTWKERTLKREAHKQVTCENSPKSPKVTGTASKKKQITPSQCKERNLQDPVPKESP KSCFFDSRSKSLPSPHPVRYFDNSSLGLCPEVQNAGAESVDSQPGPWHASSGKDVPECKT Q
- Number of residues
- 2701
- Molecular Weight
- 316413.1
- Theoretical pI
- 5.36
- GO Classification
- Functionsmicrotubule bindingProcesseslateral attachment of mitotic spindle microtubules to kinetochore / metaphase chromosome alignment / microtubule plus-end directed mitotic chromosome migration / mitotic metaphase chromosome alignment / mitotic spindle organizationComponentsintercellular bridge / intracellular membrane-bounded organelle / kinetochore microtubule / mitotic spindle / spindle midzone
- General Function
- Microtubule plus-end-directed kinetochore motor which plays an important role in chromosome congression, microtubule-kinetochore conjugation and spindle assembly checkpoint activation. Drives chromosome congression (alignment of chromosomes at the spindle equator resulting in the formation of the metaphase plate) by mediating the lateral sliding of polar chromosomes along spindle microtubules towards the spindle equator and by aiding the establishment and maintenance of connections between kinetochores and spindle microtubules (PubMed:23891108, PubMed:25395579, PubMed:7889940). The transport of pole-proximal chromosomes towards the spindle equator is favored by microtubule tracks that are detyrosinated (PubMed:25908662). Acts as a processive bi-directional tracker of dynamic microtubule tips; after chromosomes have congressed, continues to play an active role at kinetochores, enhancing their links with dynamic microtubule ends (PubMed:23955301). Suppresses chromosome congression in NDC80-depleted cells and contributes positively to congression only when microtubules are stabilized (PubMed:25743205). Plays an important role in the formation of stable attachments between kinetochores and spindle microtubules (PubMed:17535814) The stabilization of kinetochore-microtubule attachment also requires CENPE-dependent localization of other proteins to the kinetochore including BUB1B, MAD1 and MAD2. Plays a role in spindle assembly checkpoint activation (SAC) via its interaction with BUB1B resulting in the activation of its kinase activity, which is important for activating SAC. Necessary for the mitotic checkpoint signal at individual kinetochores to prevent aneuploidy due to single chromosome loss (By similarity)
- Specific Function
- ATP binding
- Pfam Domain Function
- Kinesin (PF00225)
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Chromosome, centromere, kinetochore
- Gene sequence
>lcl|BSEQ0012404|Centromere-associated protein E (CENPE) ATGGCGGAGGAAGGAGCCGTGGCCGTCTGCGTGCGAGTGCGGCCGCTGAACAGCAGAGAA GAATCACTTGGAGAAACTGCCCAAGTTTACTGGAAAACTGACAATAATGTCATTTATCAA GTTGATGGAAGTAAATCCTTCAATTTTGATCGTGTCTTTCATGGTAATGAAACTACCAAA AATGTGTATGAAGAAATAGCAGCACCAATCATCGATTCTGCCATACAAGGCTACAATGGT ACTATATTTGCCTATGGACAGACTGCTTCAGGAAAAACATATACCATGATGGGTTCAGAA GATCATTTGGGAGTTATACCCAGGGCAATTCATGACATTTTCCAAAAAATTAAGAAGTTT CCTGATAGGGAATTTCTCTTACGTGTATCTTACATGGAAATATACAATGAAACCATTACA GATTTACTCTGTGGCACTCAAAAAATGAAACCTTTAATTATTCGAGAAGATGTCAATAGG AATGTGTATGTTGCTGATCTCACAGAAGAAGTTGTATATACATCAGAAATGGCTTTGAAA TGGATTACAAAGGGAGAAAAGAGCAGGCATTATGGAGAAACAAAAATGAATCAAAGAAGC AGTCGTTCTCATACCATCTTTAGGATGATTTTGGAAAGCAGAGAGAAGGGTGAACCTTCT AATTGTGAAGGATCTGTTAAGGTATCCCATTTGAATTTGGTTGATCTTGCAGGCAGTGAA AGAGCTGCTCAAACAGGCGCTGCAGGTGTGCGGCTCAAGGAAGGCTGTAATATAAATCGA AGCTTATTTATTTTGGGACAAGTGATCAAGAAACTTAGTGATGGACAAGTTGGTGGTTTC ATAAATTATCGAGATAGCAAGTTAACACGAATTCTCCAGAATTCCTTGGGAGGAAATGCA AAGACACGTATTATCTGCACAATTACTCCAGTATCTTTTGATGAAACACTTACTGCTCTC CAGTTTGCCAGTACTGCTAAATATATGAAGAATACTCCTTATGTTAATGAGGTATCAACT GATGAAGCTCTCCTGAAAAGGTATAGAAAAGAAATAATGGATCTTAAAAAACAATTAGAG GAGGTTTCTTTAGAGACGCGGGCTCAGGCAATGGAAAAAGACCAATTGGCCCAACTTTTG GAAGAAAAAGATTTGCTTCAGAAAGTACAGAATGAGAAAATTGAAAACTTAACACGGATG CTGGTGACCTCTTCTTCCCTCACGTTGCAACAGGAATTAAAGGCTAAAAGAAAACGAAGA GTTACTTGGTGCCTTGGCAAAATTAACAAAATGAAGAACTCAAACTATGCAGATCAATTT AATATACCAACAAATATAACAACAAAAACACATAAGCTTTCTATAAATTTATTACGAGAA ATTGATGAATCTGTCTGTTCAGAGTCTGATGTTTTCAGTAACACTCTTGATACATTAAGT GAGATAGAATGGAATCCAGCAACAAAGCTACTAAATCAGGAGAATATAGAAAGTGAGTTG AACTCACTTCGTGCTGACTATGATAATCTGGTATTAGACTATGAACAACTACGAACAGAA AAAGAAGAAATGGAATTGAAATTAAAAGAAAAGAATGATTTGGATGAATTTGAGGCTCTA GAAAGAAAAACTAAAAAAGATCAAGAGAATGAACTCAGTTCAAAAGTAGAGCTGCTTAGA GAAAAGGAAGACCAGATTAAGAAGCTACAGGAATACATAGACTCTCAAAAGCTAGAAAAT ATAAAAATGGACTTGTCATACTCATTGGAAAGCATTGAAGACCCAAAACAAATGAAGCAG ACTCTGTTTGATGCTGAAACTGTAGCCCTTGATGCCAAGAGAGAATCAGCCTTTCTTAGA AGTGAAAATCTGGAGCTGAAGGAGAAAATGAAAGAACTTGCAACTACATACAAGCAAATG GAAAATGATATTCAGTTATATCAAAGCCAGTTGGAGGCAAAAAAGAAAATGCAAGTTGAT CTGGAGAAAGAATTACAATCTGCTTTTAATGAGATAACAAAACTCACCTCCCTTATAGAT GGCAAAGTTCCAAAAGATTTGCTCTGTAATTTGGAATTGGAAGGAAAGATTACTGATCTT CAGAAAGAACTAAATAAAGAAGTTGAAGAAAATGAAGCTTTGCGGGAAGAAGTCATTTTG CTTTCAGAATTGAAATCTTTACCTTCTGAAGTAGAAAGGCTGAGGAAAGAGATACAAGAC AAATCTGAAGAGCTCCATATAATAACATCAGAAAAAGATAAATTGTTTTCTGAAGTAGTT CATAAGGAGAGTAGAGTTCAAGGTTTACTTGAAGAAATTGGGAAAACAAAAGATGACCTA GCAACTACACAGTCGAATTATAAAAGCACTGATCAAGAATTCCAAAATTTCAAAACCCTT CATATGGACTTTGAGCAAAAGTATAAGATGGTCCTTGAGGAGAATGAGAGAATGAATCAG GAAATAGTTAATCTCTCTAAAGAAGCCCAAAAATTTGATTCGAGTTTGGGTGCTTTGAAG ACCGAGCTTTCTTACAAGACCCAAGAACTTCAGGAGAAAACACGTGAGGTTCAAGAAAGA CTAAATGAGATGGAACAGCTGAAGGAACAATTAGAAAATAGAGATTCTACGCTGCAAACT GTAGAAAGGGAGAAAACACTGATTACTGAGAAACTGCAGCAAACTTTAGAAGAAGTAAAA ACTTTAACTCAAGAAAAAGATGATCTAAAACAACTCCAAGAAAGCTTGCAAATTGAGAGG GACCAACTCAAAAGTGATATTCACGATACTGTTAACATGAATATAGATACTCAAGAACAA TTACGAAATGCTCTTGAGTCTCTGAAACAACATCAAGAAACAATTAATACACTAAAATCG AAAATTTCTGAGGAAGTTTCCAGGAATTTGCATATGGAGGAAAATACAGGAGAAACTAAA GATGAATTTCAGCAAAAGATGGTTGGCATAGATAAAAAACAGGATTTGGAAGCTAAAAAT ACCCAAACACTAACTGCAGATGTTAAGGATAATGAGATAATTGAGCAACAAAGGAAGATA TTTTCTTTAATACAGGAGAAAAATGAACTCCAACAAATGTTAGAGAGTGTTATAGCAGAA AAGGAACAATTGAAGACTGACCTAAAGGAAAATATTGAAATGACCATTGAAAACCAGGAA GAATTAAGACTTCTTGGGGATGAACTTAAAAAGCAACAAGAGATAGTTGCACAAGAAAAG AACCATGCCATAAAGAAAGAAGGAGAGCTTTCTAGGACCTGTGACAGACTGGCAGAAGTT GAAGAAAAACTAAAGGAAAAGAGCCAGCAACTCCAAGAAAAACAGCAACAACTTCTTAAT GTACAAGAAGAGATGAGTGAGATGCAGAAAAAGATTAATGAAATAGAGAATTTAAAGAAT GAATTAAAGAACAAAGAATTGACATTGGAACATATGGAAACAGAGAGGCTTGAGTTGGCT CAGAAACTTAATGAAAATTATGAGGAAGTGAAATCTATAACCAAAGAAAGAAAAGTTCTA AAGGAATTACAGAAGTCATTTGAAACAGAGAGAGACCACCTTAGAGGATATATAAGAGAA ATTGAAGCTACAGGCCTACAAACCAAAGAAGAACTAAAAATTGCTCATATTCACCTAAAA GAACACCAAGAAACTATTGATGAACTAAGAAGAAGCGTATCTGAGAAGACAGCTCAAATA ATAAATACTCAGGACTTAGAAAAATCCCATACCAAATTACAAGAAGAGATCCCAGTGCTT CATGAGGAACAAGAGTTACTGCCTAATGTGAAAGAAGTCAGTGAGACTCAGGAAACAATG AATGAACTGGAGTTATTAACAGAACAGTCCACAACCAAGGACTCAACAACACTGGCAAGA ATAGAAATGGAAAGGCTCAGGTTGAATGAAAAATTTCAAGAAAGTCAGGAAGAGATAAAA TCTCTAACCAAGGAAAGAGACAACCTTAAAACGATAAAAGAAGCCCTTGAAGTTAAACAT GACCAGCTGAAAGAACATATTAGAGAAACTTTGGCTAAAATCCAGGAGTCTCAAAGCAAA CAAGAACAGTCCTTAAATATGAAAGAAAAAGACAATGAAACTACCAAAATCGTGAGTGAG ATGGAGCAATTCAAACCCAAAGATTCAGCACTACTAAGGATAGAAATAGAAATGCTCGGA TTGTCCAAAAGACTTCAAGAAAGTCATGATGAAATGAAATCTGTAGCTAAGGAGAAAGAT GACCTACAGAGGCTGCAAGAAGTTCTTCAATCTGAAAGTGACCAGCTCAAAGAAAACATA AAAGAAATTGTAGCTAAACACCTGGAAACTGAAGAGGAACTTAAAGTTGCTCATTGTTGC CTGAAAGAACAAGAGGAAACTATTAATGAGTTAAGAGTGAATCTTTCAGAGAAGGAAACT GAAATATCAACCATTCAAAAGCAGTTAGAAGCAATCAATGATAAATTACAGAACAAGATC CAAGAGATTTATGAGAAAGAGGAACAATTTAATATAAAACAAATTAGTGAGGTTCAGGAA AAAGTGAATGAACTGAAACAATTCAAGGAGCATCGCAAAGCCAAGGATTCAGCACTACAA AGTATAGAAAGTAAGATGCTCGAGTTGACCAACAGACTTCAAGAAAGTCAAGAAGAAATA CAAATTATGATTAAGGAAAAAGAGGAAATGAAAAGAGTACAGGAGGCCCTTCAGATAGAG AGAGACCAACTGAAAGAAAACACTAAAGAAATTGTAGCTAAAATGAAAGAATCTCAAGAA AAAGAATATCAGTTTCTTAAGATGACAGCTGTCAATGAGACTCAGGAGAAAATGTGTGAA ATAGAACACTTGAAGGAGCAATTTGAGACCCAGAAGTTAAACCTGGAAAACATAGAAACG GAGAATATAAGGTTGACTCAGATACTACATGAAAACCTTGAAGAAATGAGATCTGTAACA AAAGAAAGAGATGACCTTAGGAGTGTGGAGGAGACTCTCAAAGTAGAGAGAGACCAGCTC AAGGAAAACCTTAGAGAAACTATAACTAGAGACCTAGAAAAACAAGAGGAGCTAAAAATT GTTCACATGCATCTGAAGGAGCACCAAGAAACTATTGATAAACTAAGAGGGATTGTTTCA GAGAAAACAAATGAAATATCAAATATGCAAAAGGACTTAGAACACTCAAATGATGCCTTA AAAGCACAGGATCTGAAAATACAAGAGGAACTAAGAATTGCTCACATGCATCTGAAAGAG CAGCAGGAAACTATTGACAAACTCAGAGGAATTGTTTCTGAGAAGACAGATAAACTATCA AATATGCAAAAAGATTTAGAAAATTCAAATGCTAAATTACAAGAAAAGATTCAAGAACTT AAGGCAAATGAACATCAACTTATTACGTTAAAAAAAGATGTCAATGAGACACAGAAAAAA GTGTCTGAAATGGAGCAACTAAAGAAACAAATAAAAGACCAAAGCTTAACTCTGAGTAAA TTAGAAATAGAGAATTTAAATTTGGCTCAGAAACTTCATGAAAACCTTGAAGAAATGAAA TCTGTAATGAAAGAAAGAGATAATCTAAGAAGAGTAGAGGAGACACTCAAACTGGAGAGA GACCAACTCAAGGAAAGCCTGCAAGAAACCAAAGCTAGAGATCTGGAAATACAACAGGAA CTAAAAACTGCTCGTATGCTATCAAAAGAACACAAAGAAACTGTTGATAAACTTAGAGAA AAAATTTCAGAAAAGACAATTCAAATTTCAGACATTCAAAAGGATTTAGATAAATCAAAA GATGAATTACAGAAAAAGCAGGACCGACAGAACCACCAAGTAAAACCTGAAAAAAGGTTA CTAAGTGATGGACAACAGCACCTTACGGAAAGCCTGAGAGAAAAGTGCTCTAGAATAAAA GAGCTTTTGAAGAGATACTCAGAGATGGATGATCATTATGAGTGCTTGAATAGATTGTCT CTTGACTTGGAGAAGGAAATTGAATTCCAAAAAGAGCTTTCAATGAGAGTTAAAGCAAAC CTCTCACTTCCCTATTTACAAACCAAACACATTGAAAAACTTTTTACTGCAAACCAGAGA TGCTCCATGGAATTCCACAGAATCATGAAGAAACTGAAGTATGTGTTAAGCTATGTTACA AAAATAAAAGAAGAACAACATGAATCCATCAATAAATTTGAAATGGATTTTATTGATGAA GTGGAAAAGCAAAAGGAATTGCTAATTAAAATACAGCACCTTCAACAAGATTGTGATGTA CCATCCAGAGAATTAAGGGATCTCAAATTGAACCAGAATATGGATCTACATATTGAGGAA ATTCTCAAAGATTTCTCAGAAAGTGAGTTCCCTAGCATAAAGACTGAATTTCAACAAGTA CTAAGTAATAGGAAAGAAATGACACAGTTTTTGGAAGAGTGGTTAAATACTCGTTTTGAT ATAGAAAAGCTTAAAAATGGCATCCAGAAAGAAAATGATAGGATTTGTCAAGTGAATAAC TTCTTTAATAACAGAATAATTGCCATAATGAATGAATCAACAGAGTTTGAGGAAAGAAGT GCTACCATATCCAAAGAGTGGGAACAGGACCTGAAATCACTGAAAGAGAAAAATGAAAAA CTATTTAAAAACTACCAAACATTGAAGACTTCCTTGGCATCTGGTGCCCAGGTTAATCCT ACCACACAAGACAATAAGAATCCTCATGTTACATCAAGAGCTACACAGTTAACCACAGAG AAAATTCGAGAGCTGGAAAATTCACTGCATGAAGCTAAAGAAAGTGCTATGCATAAGGAA AGCAAGATTATAAAGATGCAGAAAGAACTTGAGGTGACTAATGACATAATAGCAAAACTT CAAGCCAAAGTTCATGAATCAAATAAATGCCTTGAAAAAACAAAAGAGACAATTCAAGTA CTTCAGGACAAAGTTGCTTTAGGAGCTAAGCCATATAAAGAAGAAATTGAAGATCTCAAA ATGAAGCTTGTGAAAATAGACCTAGAGAAAATGAAAAATGCCAAAGAATTTGAAAAGGAA ATCAGTGCTACAAAAGCCACTGTAGAATATCAAAAGGAAGTTATAAGGCTATTGAGAGAA AATCTCAGAAGAAGTCAACAGGCCCAAGATACCTCAGTGATATCAGAACATACTGATCCT CAGCCTTCAAATAAACCCTTAACTTGTGGAGGTGGCAGCGGCATTGTACAAAACACAAAA GCTCTTATTTTGAAAAGTGAACATATAAGGCTAGAAAAAGAAATTTCTAAGTTAAAGCAG CAAAATGAACAGCTAATAAAACAAAAGAATGAATTGTTAAGCAATAATCAGCATCTTTCC AATGAGGTCAAAACTTGGAAGGAAAGAACCCTTAAAAGAGAGGCTCACAAACAAGTAACT TGTGAGAATTCTCCAAAGTCTCCTAAAGTGACTGGAACAGCTTCTAAAAAGAAACAAATT ACACCCTCTCAATGCAAGGAACGGAATTTACAAGATCCTGTGCCAAAGGAATCACCAAAA TCTTGTTTTTTTGATAGCCGATCAAAGTCTTTACCATCACCTCATCCAGTTCGCTATTTT GATAACTCAAGTTTAGGCCTTTGTCCAGAGGTGCAAAATGCAGGAGCAGAGAGTGTGGAT TCTCAGCCAGGTCCTTGGCACGCCTCCTCAGGCAAGGATGTGCCTGAGTGCAAAACTCAG TAG
- Chromosome Location
- 4
- Locus
- 4q24
- External Identifiers
Resource Link UniProtKB ID Q02224 UniProtKB Entry Name CENPE_HUMAN GenBank Gene ID CH471057 GeneCard ID CENPE GenAtlas ID CENPE HGNC ID HGNC:1856 PDB ID(s) 1T5C, 5JVP, 6M4I, 8HFH, 8OWI KEGG ID hsa:1062 NCBI Gene ID 1062 - General References
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Associated Data
- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details GSK-923295 investigational unknown target Details