Gag polyprotein

BE0003437ProteinHIV-1gag

Gag polyprotein Mediates, with Gag-Pol polyprotein, the essential events in virion assembly, including binding the plasma membrane, making the protein-protein interactions necessary to create spherical particles, recruiting the viral Env proteins, and packaging the genomic... It is acted on by 3 drugs in DrugBank.

Gene name
gag
UniProtKB entry
O93182Swiss-Prot
Cellular location
Host cell membrane
Residues / weight
500 residues · 55,674 Da
Also known as
Pr55Gag

Resolves to

Protein
UniProtO93182UniProt nameGAG_HV190
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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5+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Gag polyprotein, and which indications are they being tested in?

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