Promotilin

BE0003448ProteinHumansMLN

Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle. It is acted on by 1 drug in DrugBank.

Gene name
MLN
UniProtKB entry
P12872Swiss-Prot
Cellular location
Secreted
Residues / weight
115 residues · 12,920 Da

Resolves to

Protein
UniProtP12872UniProt nameMOTI_HUMAN
Gene
HGNCHGNC:7141NCBI Gene4295GeneCardsMLN
Pharmacology
KEGGhsa:4295
Structure
PDB1LBJPDB8IBV
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Promotilin, and which indications are they being tested in?

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