Tumor necrosis factor receptor superfamily member 11A

BE0003461ProteinHumansTNFRSF11A

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis (PubMed:9878548). It is acted on by 1 drug in DrugBank.

Gene name
TNFRSF11A
UniProtKB entry
Q9Y6Q6Swiss-Prot
Cellular location
Cell membrane
Residues / weight
616 residues · 66,033 Da
Also known as
ODFR · Osteoclast differentiation factor receptor · RANK · Receptor activator of NF-KB

Resolves to

Protein
UniProtQ9Y6Q6UniProt nameTNR11_HUMAN
Gene
HGNCHGNC:11908NCBI Gene8792GeneCardsTNFRSF11A
Pharmacology
KEGGhsa:8792
Structure
PDB1LB5
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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8Clinical trialsTrials of drugs acting on it, by phase and status
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20GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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8+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Tumor necrosis factor receptor superfamily member 11A, and which indications are they being tested in?

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