KiSS-1 receptor

BE0003468ProteinHumansKISS1R

Receptor for kisspeptins (kisspeptin-10, kisspeptin-13, kisspeptin-14 and metastin/kisspeptin-54) (PubMed:11457843, PubMed:11527393, PubMed:15020672, PubMed:15596153). It is acted on by 3 drugs in DrugBank.

Gene name
KISS1R
UniProtKB entry
Q969F8Swiss-Prot
Cellular location
Cell membrane
Residues / weight
398 residues · 42,585 Da
Also known as
AXOR12 · G protein-coupled receptor 54 · G protein-coupled receptor OT7T175 · GPR54 · hOT7T175

Resolves to

Protein
UniProtQ969F8UniProt nameKISSR_HUMAN
Gene
HGNCHGNC:4510NCBI Gene84634GeneCardsKISS1R
Pharmacology
IUPHAR/GtoPdb266KEGGhsa:84634
Structure
PDB7YQEPDB8XGOPDB8XGS
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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12GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which compounds in development act on KiSS-1 receptor, and which indications are they being tested in?

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