Pro-neuropeptide Y

BE0003476ProteinHumansNPY

Ligand for neuropeptide Y receptor type 1 (NPY1R) and neuropeptide Y receptor type 2 (NPY2R) (PubMed:1321422, PubMed:7592910, PubMed:35165283, PubMed:35507650, PubMed:36525977, PubMed:38882210). It is acted on by 3 drugs in DrugBank.

Gene name
NPY
UniProtKB entry
P01303Swiss-Prot
Cellular location
Secreted
Residues / weight
97 residues · 10,851 Da

Resolves to

Protein
UniProtP01303UniProt nameNPY_HUMAN
Gene
HGNCHGNC:7955NCBI Gene4852GeneCardsNPY
Pharmacology
KEGGhsa:4852
Structure
PDB1QFAPDB1RONPDB7RTA
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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15GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Pro-neuropeptide Y, how selective are they, and which programs against it are still in active trials?

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