HLA class I histocompatibility antigen, A alpha chain

BE0003483ProteinHumansHLA-A

Antigen-presenting major histocompatibility complex class I (MHCI) molecule. It is acted on by 5 drugs in DrugBank.

Gene name
HLA-A
UniProtKB entry
P04439Swiss-Prot
Cellular location
Membrane
Residues / weight
365 residues · 40,840 Da
Also known as
HLA class I histocompatibility antigen, A-3 alpha chain · HLA-A · HLAA · Human leukocyte antigen A · MHC class I antigen A*3

Resolves to

Protein
UniProtP04439UniProt nameHLAA_HUMAN
Gene
HGNCHGNC:4931NCBI Gene3105
Structure
PDB2XPGPDB3RL1PDB3RL2
Drugs

What you can answer from here — as of May 03, 2025

5DrugsApproved to experimental, with action, bond type and pharmacological action
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73Clinical trialsTrials of drugs acting on it, by phase and status
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25GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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14+ReferencesStructured and connected to the statements they support
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Which approved drugs act on HLA class I histocompatibility antigen, A alpha chain, how selective are they, and which programs against it are still in active trials?

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