Interleukin-15

BE0003486ProteinHumansIL15

Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems (PubMed:15123770). It is acted on by 5 drugs in DrugBank.

Gene name
IL15
UniProtKB entry
P40933Swiss-Prot
Cellular location
Secreted
Residues / weight
162 residues · 18,086 Da
Also known as
IL-15

Resolves to

Protein
UniProtP40933UniProt nameIL15_HUMAN
Gene
HGNCHGNC:5977NCBI Gene3600GeneCardsIL15
Pharmacology
KEGGhsa:3600
Structure
PDB2XQBPDB2Z3QPDB2Z3R
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
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20Clinical trialsTrials of drugs acting on it, by phase and status
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14GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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18+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-15, how selective are they, and which programs against it are still in active trials?

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