Endoglin

BE0003494ProteinHumansENG

Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis (PubMed:21737454, PubMed:23300529). It is acted on by 1 drug in DrugBank.

Gene name
ENG
UniProtKB entry
P17813Swiss-Prot
Cellular location
Cell membrane
Residues / weight
658 residues · 70,577 Da
Also known as
END

Resolves to

Protein
UniProtP17813UniProt nameEGLN_HUMAN
Gene
HGNCHGNC:3349NCBI Gene2022GeneCardsENG
Pharmacology
IUPHAR/GtoPdb2895KEGGhsa:2022
Structure
PDB5HZVPDB5HZWPDB5I04
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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13Clinical trialsTrials of drugs acting on it, by phase and status
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27GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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23+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Endoglin, and which indications are they being tested in?

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