Platelet-derived growth factor subunit B

BE0003495ProteinHumansPDGFB

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is acted on by 1 drug in DrugBank.

Gene name
PDGFB
UniProtKB entry
P01127Swiss-Prot
Cellular location
Secreted
Residues / weight
241 residues · 27,283 Da
Also known as
PDGF subunit B · PDGF-2 · PDGF2 · Platelet-derived growth factor B chain · Platelet-derived growth factor beta polypeptide

Resolves to

Protein
UniProtP01127UniProt namePDGFB_HUMAN
Gene
HGNCHGNC:8800NCBI Gene5155GeneCardsPDGFB
Pharmacology
KEGGhsa:5155
Structure
PDB1PDGPDB3MJGPDB4HQU
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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5Clinical trialsTrials of drugs acting on it, by phase and status
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52GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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26+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Platelet-derived growth factor subunit B, and which indications are they being tested in?

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