Alpha-mannosidase 2

BE0003505ProteinHumansMAN2A1

Catalyzes the first committed step in the biosynthesis of complex N-glycans. It is acted on by 9 drugs in DrugBank.

Gene name
MAN2A1
UniProtKB entry
Q16706Swiss-Prot
Cellular location
Golgi apparatus membrane
Residues / weight
1,144 residues · 131,139 Da
Also known as
3.2.1.114 · AMan II · Golgi alpha-mannosidase II · Man II · MANA2

Resolves to

Protein
UniProtQ16706UniProt nameMA2A1_HUMAN
Gene
HGNCHGNC:6824NCBI Gene4124GeneCardsMAN2A1
Pharmacology
KEGGhsa:4124
Drugs

What you can answer from here — as of September 07, 2019

9DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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16+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Alpha-mannosidase 2, and which indications are they being tested in?

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