Monocyte differentiation antigen CD14

BE0003519ProteinHumansCD14

Coreceptor for bacterial lipopolysaccharide (PubMed:1698311, PubMed:23264655). It is acted on by 3 drugs in DrugBank.

Gene name
CD14
UniProtKB entry
P08571Swiss-Prot
Cellular location
Cell membrane
Residues / weight
375 residues · 40,076 Da
Also known as
My23 antigen · Myeloid cell-specific leucine-rich glycoprotein

Resolves to

Protein
UniProtP08571UniProt nameCD14_HUMAN
Gene
HGNCHGNC:1628NCBI Gene929GeneCardsCD14
Pharmacology
KEGGhsa:929
Structure
PDB4GLP
Drugs

What you can answer from here — as of September 07, 2019

3DrugsApproved to experimental, with action, bond type and pharmacological action
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14Clinical trialsTrials of drugs acting on it, by phase and status
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11GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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25+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Monocyte differentiation antigen CD14, how selective are they, and which programs against it are still in active trials?

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