Probable peptidoglycan D,D-transpeptidase PenA

BE0003621ProteinNeisseria gonorrhoeaepenA

Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. It is acted on by 1 drug in DrugBank.

Gene name
penA
UniProtKB entry
P08149Swiss-Prot
Cellular location
Cell inner membrane
Residues / weight
581 residues · 63,650 Da
Also known as
3.4.16.4 · PBP-2 · Penicillin-binding protein 2

Resolves to

Protein
UniProtP08149UniProt namePBP2_NEIGO
Gene
GenBank150279
Structure
PDB3EQUPDB3EQVPDB4U3T
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
Sign in
10GO termsFunction, process and component, as structured annotations
Sign in
2Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
3+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Probable peptidoglycan D,D-transpeptidase PenA, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In