Peptidoglycan D,D-transpeptidase FtsI

BE0003622ProteinHaemophilus influenzaepbp3

Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. It is acted on by 1 drug in DrugBank.

Gene name
pbp3
UniProtKB entry
Q60FT7TrEMBL
Residues / weight
610 residues · 67,295 Da
Also known as
3.4.16.4 · ftsI · PBP-3 · PBP3 · Penicillin-binding protein 3

Resolves to

Protein
UniProtQ60FT7UniProt nameQ60FT7_HAEIF
Drugs

What you can answer from here — as of May 03, 2025

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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6+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Peptidoglycan D,D-transpeptidase FtsI, how selective are they, and which programs against it are still in active trials?

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