Matrix metalloproteinase-15

BE0003693ProteinHumansMMP15

Endopeptidase that degrades various components of the extracellular matrix. It is acted on by 1 drug in DrugBank.

Gene name
MMP15
UniProtKB entry
P51511Swiss-Prot
Cellular location
Membrane
Residues / weight
669 residues · 75,806 Da
Also known as
3.4.24.- · Membrane-type matrix metalloproteinase 2 · Membrane-type-2 matrix metalloproteinase · MMP-15 · MT-MMP 2

Resolves to

Protein
UniProtP51511UniProt nameMMP15_HUMAN
Gene
HGNCHGNC:7161NCBI Gene4324GenBank963056GeneCardsMMP15
Pharmacology
IUPHAR/GtoPdb1639KEGGhsa:4324
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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3GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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10+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Matrix metalloproteinase-15, and which indications are they being tested in?

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