Inorganic pyrophosphatase

BE0003737ProteinBurkholderia pseudomallei (strain 1710b)ppa

Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. It is acted on by 2 drugs in DrugBank.

Gene name
ppa
UniProtKB entry
Q3JUV5TrEMBL
Cellular location
Cytoplasm
Residues / weight
175 residues · 19,161 Da
Also known as
3.6.1.1 · PPase · Pyrophosphate phospho-hydrolase

Resolves to

Protein
UniProtQ3JUV5UniProt nameQ3JUV5_BURP1
Gene
GenBank76580589
Pharmacology
KEGGbpm:BURPS1710b_1237
Structure
PDB3D63PDB3EIYPDB3EIZ
Drugs

What you can answer from here — as of September 07, 2019

2DrugsApproved to experimental, with action, bond type and pharmacological action
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4GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Inorganic pyrophosphatase, and which indications are they being tested in?

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