2,3-diketo-5-methylthiopentyl-1-phosphate enolase

BE0003741ProteinGeobacillus kaustophilus (strain HTA426)mtnW

Catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P). It is acted on by 1 drug in DrugBank.

Gene name
mtnW
UniProtKB entry
Q5L1E2Swiss-Prot
Residues / weight
413 residues · 44,905 Da
Also known as
5.3.2.5 · DK-MTP-1-P enolase · RLP · RuBisCO-like protein

Resolves to

Protein
UniProtQ5L1E2UniProt nameMTNW_GEOKA
Gene
NCBI Gene3185264GenBank56378378
Pharmacology
KEGGgka:GK0953
Structure
PDB2OEJPDB2OEKPDB2OEL
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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6GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on 2,3-diketo-5-methylthiopentyl-1-phosphate enolase, and which indications are they being tested in?

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