Linear primary-alkylsulfatase

BE0003744ProteinPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)sdsA1

Alkylsulfatase that cleaves both short and medium-length alkylsulfates, including the widely used detergent sodium dodecyl sulfate (SDS) (PubMed:16684886). It is acted on by 2 drugs in DrugBank.

Gene name
sdsA1
UniProtKB entry
Q9I5I9TrEMBL
Residues / weight
658 residues · 72,592 Da
Also known as
3.1.6.21 · SDS hydrolase · SDS hydrolase SdsA1 · Sodium dodecyl sulfate hydrolase · Type III linear primary-alkylsulfatase

Resolves to

Protein
UniProtQ9I5I9UniProt nameLPAKS_PSEAE
Gene
NCBI Gene882069GenBank9945819
Pharmacology
KEGGpae:PA0740
Structure
PDB2CFUPDB2CFZPDB2CG2
Drugs

What you can answer from here — as of May 03, 2025

2DrugsApproved to experimental, with action, bond type and pharmacological action
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2GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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3+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Linear primary-alkylsulfatase, and which indications are they being tested in?

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