Prostasin

BE0003746ProteinHumansPRSS8

Possesses a trypsin-like cleavage specificity with a preference for poly-basic substrates. It is acted on by 1 drug in DrugBank.

Gene name
PRSS8
UniProtKB entry
Q16651Swiss-Prot
Cellular location
Cell membrane
Residues / weight
343 residues · 36,431 Da
Also known as
3.4.21.- · CAP1 · Channel-activating protease 1 · Serine protease 8

Resolves to

Protein
UniProtQ16651UniProt namePRSS8_HUMAN
Gene
HGNCHGNC:9491NCBI Gene5652GenBank862305GeneCardsPRSS8
Pharmacology
IUPHAR/GtoPdb2400KEGGhsa:5652
Structure
PDB3DFJPDB3DFLPDB3E0N
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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1GO termFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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9+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Prostasin, and which indications are they being tested in?

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