UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase

BE0003765ProteinStreptococcus pneumoniae (strain ATCC BAA-255 / R6)murF

Involved in cell wall formation. It is acted on by 1 drug in DrugBank.

Gene name
murF
UniProtKB entry
Q8DNV6TrEMBL
Cellular location
Cytoplasm
Residues / weight
457 residues · 50,502 Da
Also known as
6.3.2.10 · D-alanyl-D-alanine-adding enzyme

Resolves to

Protein
UniProtQ8DNV6UniProt nameQ8DNV6_STRR6
Gene
NCBI Gene933049GenBank15457529
Pharmacology
KEGGspr:spr1514
Structure
PDB2AM1PDB2AM2PDB3ZM5
Drugs

What you can answer from here — as of September 07, 2019

1DrugApproved to experimental, with action, bond type and pharmacological action
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9GO termsFunction, process and component, as structured annotations
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2Pfam domainsDomain architecture mapped to Pfam families and clans
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4+ReferencesStructured and connected to the statements they support
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Which compounds in development act on UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase, and which indications are they being tested in?

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