Receptor-type tyrosine-protein phosphatase beta

BE0003769ProteinHumansPTPRB

Plays an important role in blood vessel remodeling and angiogenesis. It is acted on by 5 drugs in DrugBank.

Gene name
PTPRB
UniProtKB entry
P23467Swiss-Prot
Cellular location
Membrane
Residues / weight
1,997 residues · 224,300 Da
Also known as
3.1.3.48 · Protein-tyrosine phosphatase beta · PTPB · R-PTP-beta · Vascular endothelial protein tyrosine phosphatase

Resolves to

Protein
UniProtP23467UniProt namePTPRB_HUMAN
Gene
HGNCHGNC:9665NCBI Gene5787GenBank35788GeneCardsPTPRB
Pharmacology
IUPHAR/GtoPdb1851KEGGhsa:5787
Structure
PDB2AHSPDB2H02PDB2H03
Drugs

What you can answer from here — as of September 07, 2019

5DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
8GO termsFunction, process and component, as structured annotations
Sign in
3Pfam domainsDomain architecture mapped to Pfam families and clans
Sign in
20+ReferencesStructured and connected to the statements they support
Sign in

Which compounds in development act on Receptor-type tyrosine-protein phosphatase beta, and which indications are they being tested in?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In